Lupron™

What is Lupron™?

Lupron™ (leuprolide acetate) is a gonadotropin releasing hormone agonist analogue. It is used to shut down the pituitary gland's production of various hormones which are involved in reproduction. The drug is used to help prevent premature luteinization and premature ovulation.


Preparation of Standard Lupron™ (2 week kit):

Lupron is administered subcutaneously only.


Lupron™ comes as a premixed clear liquid which comes in a multidose vial. You will use the same vial of Lupron each evening until all of the medication is gone or you are instructed to discontinue it.


The medication doses and corresponding volume to measure on the syringe is as follows:


1 milligram (mg) of Lupron = 20 Units on the insulin syringe (0.2 ml)

.75 mg = 15 Units (0.15 ml)

0.5 mg = 10 Units (0.1 ml)

0.25 mg = 5 Units (0.05 ml)


Your dose may vary during your treatment cycle.


  1. Wash your hands thoroughly and make sure that the surface you work on is clean.
  2. Use an alcohol swab to cleanse the rubber stopper of the vial.
  3. Pull the plunger of the syringe back to the appropriate marking.
  4. Pull off the cap of the needle, and pierce the rubber stopper of the Lupron vial.
  5. Push the plunger all the way in. Keeping the needle inside the bottle, turn the vial upside down. With the needle in the liquid, pull back the plunger, until the syringe fills to the proper mark.
  6. Remove the needle from the vial, and prepare to administer the injection.

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